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ECL OIE

About the database

What is APZEC?

Animal pathogenic and zoonotic E. coli (APZEC) are E. coli which are pathogenic in animals or which are harmless in the animal reservoir but are potentially pathogenic in humans.

The APZEC approach

Isolates are examined for the detection of the presence of 20 virulence genes associated with the most important pathotypes causing disease in animals. Antimicrobial resistance is also determined, and demographic and clinical data are gathered resulting in an integrated profile.

What is the APZEC Database?

The APZEC Database is an epidemiological tool providing an overview of virotypes and antimicrobial resistance of pathogenic E. coli in animals, based on virulence gene profiles, and antimicrobial resistance of pathogenic E. coli from clinical cases and healthy animals at the farm and abattoir level in prevalence studies worldwide.

Why the APZEC Database?

The database serves as an indicator of animal health and as a tool for monitoring trends in virulence and antimicrobial resistance in APZEC. More specifically, it will provide guidance in the setting up of appropriate strategies for the diagnosis and control of infection in animals on-farm and in the evaluation of the effectiveness of these strategies.

How the database works

The database, regularly updated from 2008, currently contains data for over 2,500 isolates from all production and companion animal species, mostly from clinical cases of pigs, cattle, and poultry on a worldwide basis. Data are accessible as interactive charts and an interactive mapping system. Protocols and primers used for the generation of the isolate data, and control strains used in the described procedures are also available on this website.

More about the APZEC Database:

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